Cartilage types: a)Hyaline Cartilage


1. Composition
Fibers, Hyaline cartilage matrix contains thin fibrils of type II collagen. Their small size and their refractive index (close to that of the ground substance) make them difficult to distinguish with the light microscope. Type II collagen contains a higher proportion of hydroxylysine than does type I. b. Ground substance, the predominant tissue component, comprises the following: (1) GAGs, mostly chondroitin sulfates and hyaluronic acid, with smaller amounts of keratan sulfate and heparan sulfate
(2) Proteoglycans, core proteins with GAG side chains;
(3) Proteoglycan aggregates proteoglycans covalently linked to long chains of hyaluronic acid by link protein;
(4) Glycoproteins, which attach various matrix components to one another and cells to the matrix, including link protein, fibronectin, chondronectin; and (5) Tissue fluid, an ultrafiltrate of blood plasma.

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