cartilage physiology histology

Building

Schematic example of a Chondrons

As Chondroblasten come cartilage cells, chondrocytes, and Chondroklasten before. As Chondroblasten ( "Knorpelbildner"), the precursor cells called chondrocytes. They come from mesenchymal stem cells and make the active form of cartilage cells, because they all components of cartilage matrix can synthesize. Once this synthesis function they have, they differentiate into the chondrocytes, the actual cartilage cells. The chondrocytes are smaller than the Chondroblasten, spherical shape, have a rounded nucleus and contain lots of water, fat and glycogen. Their number, location and density for each Knorpelart specific. Chondrocytes are still in the immature state divide, which is characteristic appearance of "isogenic groups" may lead. They arise when the dividing cells already surrounded by cartilage matrix and are thus no longer differentiate between soft can. The groups are isogenic chondrocyte complexes, where each complex from a single chondrocytes arose. The individual complexes seem from a cartilage capsule to be surrounded and cartilage in a cave (Lacuna) to lie, but only when the fixation arises and the originally received by the chondrocytes reflects place. That includes a Knorpelhof, who through his property basophils anfärbbar is clear (territory). The isogenic groups are usually arranged columnar. The isogenic group and their territory summarizes it as "Chondron" together. Once the chondrocytes are differentiated, they lose their ability to divide. Chondroklasten known as scavenger cells in turn, focusing on specialized cartilage. They are much larger and merger of several monocytes and thus arose mostly Multinucleated giant cells. They play the main role in the degradation of early cartilage bones model (chondrale ossification) to the bone or later, in this context, including the healing of fractures.